The Two Leading GLP-1 Weight Loss Medications
Both semaglutide (Wegovy) and tirzepatide (Zepbound) are highly effective — but they work differently and may produce different results.
| Metric | Semaglutide | Tirzepatide |
|---|---|---|
| Avg Weight Loss | ~15% | ~22% |
| Patients ≥20% loss | ~32% | ~57% |
| FDA Approval | 2021 | 2023 |
| Dosing | Weekly injection | Weekly injection |
The choice should be made with your medical provider based on your health profile, insurance coverage, treatment goals, and how your body responds.
More Comparisons
GLP-1 Medications vs. Traditional Weight Loss ProgramsWegovy vs. Zepbound: Comparing Your OptionsGLP-1 Medication vs. Weight-Loss Surgery
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